| Previous day | Saturday 21 May 2016 | Next day |
| New Mexico 11 at Air Force 2 | Recap | |
| South Carolina 9 at Alabama 7 | Recap | |
| Longwood 6 at Appalachian State 8 | makeup of 5/20 game | |
| Longwood 2 at Appalachian State 3 (8) | Recap | |
| Arkansas State 15 at Arkansas-Little Rock 11 | Recap | |
| Oklahoma 7 at Austin Peay State 17 | Recap | |
| Maine 12 at Binghamton 7 | Recap | |
| Santa Clara 5 at Brigham Young 10 | Recap | |
| Bowling Green State 3 at Buffalo 8 | Recap | |
| Seton Hall 5 at Butler 2 | Recap | |
| North Dakota 2 at Cal State Bakersfield 16 (7) | Recap | |
| Hawaii 3 at Cal State Fullerton 8 | Recap | |
| Seattle 6 at Cal State Sacramento 3 | Recap | |
| Utah 8 at California 3 | Recap | |
| Southeastern Louisiana 2 at Central Arkansas 3 | Recap | |
| Wagner 4 at Central Connecticut State 6 (12) | Recap | |
| East Carolina 8 at Central Florida 7 | Recap | |
| Western Michigan 1 at Central Michigan 3 | Recap | |
| Utah Valley State 14 at Chicago State 2 (7) | Recap | |
| Campbell 4 at Coastal Carolina 23 (7) | Recap | |
| William and Mary 0 at College of Charleston 6 | Recap | |
| Virginia Commonwealth 5 at Davidson 11 | Recap | |
| Virginia Commonwealth at Davidson | "CCD, inclement weather (makeup of 5/20 game)" | |
| The Citadel 6 at East Tennessee State 10 | Recap | |
| Southern Illinois-Edwardsville 6 at Eastern Illinois 11 | Recap | |
| Richmond at Elon | "CCD, inclement weather" | |
| Western Kentucky 1 at Florida Atlantic 4 | Resumption of 5/20 game | |
| Kennesaw State 8 at Florida Gulf Coast 7 | Recap | |
| Southern Mississippi 8 at Florida International 13 | Recap | |
| Miami Florida 2 at Florida State 3 (10) | makeup of 5/20 game | |
| Miami Florida 8 at Florida State 5 | Recap | |
| San Francisco 6 at Fresno State 3 | Recap | |
| Wofford 1 at Furman 5 | Recap | |
| Wofford 13 at Furman 5 | makeup of 5/20 game | |
| Winthrop 7 at Gardner-Webb 4 | makeup of 5/20 game | |
| Tennessee 5 at Georgia 2 | Recap | |
| Georgia State 1 at Georgia Southern 5 | Recap | |
| Boston College 7 at Georgia Tech 6 | makeup of 5/20 game | |
| Boston College 8 at Georgia Tech 3 | Recap | |
| Tulane 4 at Houston 3 | Recap | |
| Western Illinois 3 at IUPU-Fort Wayne 6 | Recap | |
| Michigan 3 at Illinois 6 | Recap | |
| Wright State 12 at Illinois-Chicago 5 | Recap | |
| Evansville 0 at Indiana State 3 | Recap | |
| Tennessee-Martin 5 at Jacksonville State 9 | Recap | |
| Western Carolina at Kent State | "CCD, inclement weather" | |
| Missouri 2 at Kentucky 7 | Recap | |
| Florida 3 at Louisiana State 7 | Resumption of 5/19 game | |
| Florida 6 at Louisiana State 2 (7) | Recap | |
| Rice 5 at Louisiana Tech 10 | Recap | |
| Louisiana-Monroe 2 at Louisiana-Lafayette 6 | Recap | |
| Old Dominion 6 at Marshall 5 | Recap | |
| Hartford 4 at Maryland-Baltimore County 13 | Recap | |
| George Mason 2 at Massachusetts 4 | Recap | |
| Cincinnati 4 at Memphis 3 (10) | Recap | |
| Maryland 6 at Michigan State 4 | Recap | |
| Texas-San Antonio 4 at Middle Tennessee State 3 | Recap | |
| Ohio State 6 at Minnesota 5 (10) | Recap | |
| Arkansas 4 at Mississippi State 9 | Recap | |
| Illinois State 2 at Missouri State 5 | Recap | |
| Massachusetts-Lowell at Monmouth | "CCD, impending weather" | |
| Morehead State 4 at Murray State 5 | Recap | |
| Holy Cross vs Navy | "PPD to 5/22, field conditions (Patriot Championship, Game 1, Annapolis, MD)" | |
| Indiana 0 at Nebraska 3 | Recap | |
| Oral Roberts 5 at Nebraska-Omaha 11 | Recap | |
| Nevada-Las Vegas 7 at Nevada 9 | Recap | |
| Nicholls State 11 at New Orleans 5 | Recap | |
| North Carolina 1 at North Carolina State 10 | Recap | |
| Alabama-Birmingham 11 at North Carolina-Charlotte 8 | makeup of 5/19 game | |
| Alabama-Birmingham 4 at North Carolina-Charlotte 6 (7) | makeup of 5/20 game | |
| South Dakota State 7 at North Dakota State 4 | Recap | |
| Towson 7 at Northeastern 4 | Recap | |
| New Mexico State 3 at Northern Colorado 6 | Recap | |
| Abilene Christian 3 at Northwestern State 4 | Recap | |
| Clemson 6 at Notre Dame 2 | Recap | |
| Wisconsin-Milwaukee 5 at Oakland 6 (10) | Recap | |
| Kansas 1 at Oklahoma State 8 | Recap | |
| Arizona 2 at Oregon 4 | Recap | |
| Pacific 0 at Pepperdine 3 | Recap | |
| Duke at Pittsburgh | "CCD, inclement weather" | |
| Charleston Southern 9 at Presbyterian 4 | makeup of 5/19 game | |
| Cal State Northridge 6 at Purdue 0 | Recap | |
| Northwestern 7 at Rutgers 10 | Recap | |
| Long Island 12 at Sacred Heart 2 (7) | Recap | |
| Long Island 4 at Sacred Heart 0 (7) | Recap | |
| Houston Baptist 4 at Sam Houston State 5 | Recap | |
| Virginia Military 6 at Samford 5 (10) | "moved from 5/20, impending weather" | |
| Gonzaga 4 at San Diego 10 | Recap | |
| San Diego State 6 at San Jose State 0 (5) | "5 innings, rain" | |
| Jacksonville 12 at South Carolina-Upstate 3 (7) | makeup of 5/20 game | |
| Jacksonville 2 at South Carolina-Upstate 3 | Recap | |
| Connecticut 3 at South Florida 2 | Recap | |
| Belmont 6 at Southeast Missouri State 5 | Recap | |
| Oregon State 1 at Southern California 10 | Recap | |
| Bradley 2 at Southern Illinois 1 | Recap | |
| Creighton 2 at St John's 6 | Recap | |
| George Washington 5 at St Louis 8 | Recap | |
| Lamar 12 at Stephen F. Austin 0 (7) | Recap | |
| Lipscomb 6 at Stetson 1 | Recap | |
| Albany 0 at Stony Brook 4 | Recap | |
| Albany 1 at Stony Brook 0 (7) | Recap | |
| Eastern Kentucky 5 at Tennessee Tech 7 | Recap | |
| Baylor 6 at Texas 7 | Recap | |
| Mississippi 3 at Texas A&M 2 | Recap | |
| Incarnate Word at Texas A&M-Corpus Christi | "CCD, field conditions (makeup of 5/19 game)" | |
| Incarnate Word at Texas A&M-Corpus Christi | "CCD, field conditions" | |
| Kansas State 3 at Texas Christian 9 | Recap | |
| West Virginia 8 at Texas Tech 7 | Recap | |
| Texas State 6 at Texas-Arlington 2 | Recap | |
| Eastern Michigan 2 at Toledo 14 | Recap | |
| South Alabama 0 at Troy 8 | Recap | |
| Long Beach State 14 at UC Davis 1 | Recap | |
| UC Santa Barbara 4 at UC Irvine 5 | Recap | |
| Cal Poly 5 at UC Riverside 11 | Recap | |
| Arizona State 2 at UCLA 13 | Recap | |
| Grand Canyon 3 at UT Rio Grande Valley 4 | Recap | |
| Youngstown State 5 at Valparaiso 7 | Recap | |
| Auburn 3 at Vanderbilt 4 | Recap | |
| Virginia Tech 1 at Virginia 4 | Recap | |
| Louisville 9 at Wake Forest 4 | Recap | |
| Stanford 8 at Washington 7 (12) | Recap | |
| McNeese State 9 at Washington State 12 | Recap | |
| Dallas Baptist 3 at Wichita State 4 | Recap | |
| Villanova 0 at Xavier 9 | Recap |