| 5 Nov | Virginia Tech 67 | at | Clemson 60 | |||
| 7 Nov | Presbyterian 45 | at | Clemson 79 | vs BSo | ||
| 10 Nov | Colgate 68 | at | Clemson 81 | vs PL | ||
| 17 Nov | Detroit 65 | at | Clemson 87 | vs HL | ||
| 21 Nov | Alabama A&M 51 | at | Clemson 87 | vs SWAC | ||
| 24 Nov | Clemson 62 | vs | TCU 60 | OT | Las Vegas, NV | vs B12 |
| 26 Nov | Colorado 71 | vs | Clemson 67 | Las Vegas, NV | vs P12 | |
| 2 Dec | Clemson 60 | at | Minnesota 78 | at B10 | ||
| 8 Dec | Clemson 53 | at | Florida St 72 | |||
| 15 Dec | South Carolina 67 | at | Clemson 54 | vs SEC | ||
| 20 Dec | Jacksonville 39 | at | Clemson 68 | vs ASUN | ||
| 22 Dec | Yale 54 | at | Clemson 45 | vs Ivy | ||
| 31 Dec | Miami FL 73 | at | Clemson 68 | OT | ||
| 4 Jan | NC State 70 | at | Clemson 81 | |||
| 11 Jan | Clemson 79 | at | North Carolina 76 | OT | ||
| 14 Jan | Duke 72 | at | Clemson 79 | |||
| 18 Jan | Clemson | at | NC State | |||
| 21 Jan | Wake Forest | at | Clemson | |||
| 25 Jan | Clemson | at | Louisville | |||
| 28 Jan | Syracuse | at | Clemson | |||
| 1 Feb | Clemson | at | Wake Forest | |||
| 5 Feb | Clemson | at | Virginia | |||
| 9 Feb | Notre Dame | at | Clemson | |||
| 12 Feb | Clemson | at | Pittsburgh | |||
| 15 Feb | Louisville | at | Clemson | |||
| 22 Feb | Clemson | at | Boston College | |||
| 25 Feb | Clemson | at | Georgia Tech | |||
| 29 Feb | Florida St | at | Clemson | |||
| 4 Mar | Clemson | at | Virginia Tech | |||
| 6 Mar | Georgia Tech | at | Clemson |
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