| 5 Nov | UC Davis 48 | at | Loyola-Chicago 82 | vs BWC | ||
| 8 Nov | Loyola-Chicago 63 | at | Furman 87 | at SC | ||
| 12 Nov | Coppin St 76 | at | Loyola-Chicago 72 | vs MEAC | ||
| 16 Nov | St Joseph's PA 68 | at | Loyola-Chicago 85 | vs A10 | ||
| 20 Nov | IUPUI 62 | at | Loyola-Chicago 85 | vs HL | ||
| 25 Nov | South Florida 66 | vs | Loyola-Chicago 55 | George Town, Cayman Islands | vs AAC | |
| 26 Nov | Colorado St 61 | vs | Loyola-Chicago 60 | George Town, CAY | vs MWC | |
| 27 Nov | Loyola-Chicago 68 | vs | Old Dominion 61 | George Town, CAY | vs CUSA | |
| 3 Dec | Loyola-Chicago 70 | at | Ball St 58 | at MAC | ||
| 7 Dec | Quincy 59 | at | Loyola-Chicago 90 | vs ND1 | ||
| 15 Dec | Norfolk St 45 | at | Loyola-Chicago 64 | vs MEAC | ||
| 18 Dec | Loyola-Chicago 78 | vs | Vanderbilt 70 | Phoenix, AZ | vs SEC | |
| 22 Dec | Davidson 59 | at | Loyola-Chicago 56 | vs A10 | ||
| 30 Dec | Loyola-Chicago 66 | at | Valparaiso 63 | |||
| 4 Jan | Missouri St 58 | at | Loyola-Chicago 62 | |||
| 7 Jan | Loyola-Chicago 62 | at | Drake 65 | |||
| 11 Jan | Evansville 44 | at | Loyola-Chicago 78 | |||
| 16 Jan | S Illinois 48 | at | Loyola-Chicago 64 | |||
| 19 Jan | Loyola-Chicago | at | Illinois St | |||
| 22 Jan | Indiana St | at | Loyola-Chicago | |||
| 26 Jan | Loyola-Chicago | at | Northern Iowa | |||
| 29 Jan | Loyola-Chicago | at | S Illinois | |||
| 1 Feb | Bradley | at | Loyola-Chicago | |||
| 5 Feb | Loyola-Chicago | at | Indiana St | |||
| 9 Feb | Valparaiso | at | Loyola-Chicago | |||
| 12 Feb | Loyola-Chicago | at | Evansville | |||
| 15 Feb | Northern Iowa | at | Loyola-Chicago | |||
| 19 Feb | Illinois St | at | Loyola-Chicago | |||
| 22 Feb | Loyola-Chicago | at | Missouri St | |||
| 25 Feb | Drake | at | Loyola-Chicago | |||
| 29 Feb | Loyola-Chicago | at | Bradley |
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