| 5 Nov | Nicholls St 70 | at | Illinois 78 | OT | at B10 | |
| 9 Nov | Nicholls St 75 | at | Pittsburgh 70 | at ACC | ||
| 13 Nov | Paul Quinn 66 | at | Nicholls St 81 | vs ND1 | ||
| 16 Nov | Nicholls St 65 | at | LSU 75 | at SEC | ||
| 19 Nov | Nicholls St 65 | at | Rhode Island 70 | at A10 | ||
| 22 Nov | NC A&T 66 | vs | Nicholls St 54 | St. James, Jamaica | vs MEAC | |
| 24 Nov | Nicholls St 82 | vs | UMBC 72 | St. James, Jamaica | vs AEC | |
| 26 Nov | Blue Mtn 56 | at | Nicholls St 102 | vs ND1 | ||
| 2 Dec | Camp U-Harrodsburg 69 | at | Nicholls St 120 | vs ND1 | ||
| 11 Dec | Carver Bib 44 | at | Nicholls St 118 | vs ND1 | ||
| 14 Dec | Nicholls St 57 | at | West Virginia 83 | at B12 | ||
| 18 Dec | TAM C. Christi 58 | at | Nicholls St 64 | |||
| 21 Dec | Nicholls St 61 | at | Abilene Chr 79 | |||
| 2 Jan | Incarnate Word 60 | at | Nicholls St 76 | |||
| 4 Jan | Nicholls St 70 | at | Sam Houston St 58 | |||
| 8 Jan | Nicholls St 61 | at | Lamar 52 | |||
| 11 Jan | Nicholls St 69 | at | SE Louisiana 58 | |||
| 15 Jan | Northwestern LA 73 | at | Nicholls St 72 | |||
| 18 Jan | Cent Arkansas | at | Nicholls St | |||
| 22 Jan | Houston Bap | at | Nicholls St | |||
| 25 Jan | Nicholls St | at | New Orleans | |||
| 29 Jan | Nicholls St | at | McNeese St | |||
| 5 Feb | Nicholls St | at | SF Austin | |||
| 8 Feb | Sam Houston St | at | Nicholls St | |||
| 12 Feb | Lamar | at | Nicholls St | |||
| 15 Feb | SE Louisiana | at | Nicholls St | |||
| 19 Feb | Nicholls St | at | Northwestern LA | |||
| 22 Feb | Nicholls St | at | Cent Arkansas | |||
| 26 Feb | Nicholls St | at | Houston Bap | |||
| 29 Feb | New Orleans | at | Nicholls St | |||
| 4 Mar | McNeese St | at | Nicholls St |
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