| 5 Nov | UC Irvine 76 | at | San Diego 73 | at WCC | ||
| 9 Nov | UC Irvine 73 | at | Pepperdine 77 | at WCC | ||
| 12 Nov | Life Pacific 52 | at | UC Irvine 98 | vs ND1 | ||
| 15 Nov | UC Irvine 69 | at | Boise St 60 | at MWC | ||
| 18 Nov | UC Irvine 53 | at | Colorado 69 | at P12 | ||
| 21 Nov | UC Irvine 58 | at | TCU 59 | at B12 | ||
| 24 Nov | Detroit 86 | vs | UC Irvine 74 | Las Vegas, NV | vs HL | |
| 26 Nov | UC Irvine 92 | vs | Louisiana 67 | Las Vegas, NV | vs SBC | |
| 30 Nov | E Michigan 56 | at | UC Irvine 77 | vs MAC | ||
| 7 Dec | Cal Baptist 68 | at | UC Irvine 60 | vs WAC | ||
| 14 Dec | Pacific Union 63 | at | UC Irvine 120 | vs ND1 | ||
| 16 Dec | UC Irvine 74 | vs | Kent 68 | El Paso, TX | vs MAC | |
| 17 Dec | UC Irvine 61 | at | UTEP 67 | at CUSA | ||
| 20 Dec | UC Irvine 67 | at | IL Chicago 76 | at HL | ||
| 28 Dec | Pacific 56 | at | UC Irvine 69 | vs WCC | ||
| 4 Jan | UC Irvine 73 | at | Harvard 77 | at Ivy | ||
| 11 Jan | Hawaii 60 | at | UC Irvine 74 | |||
| 15 Jan | UC Irvine 74 | at | CS Fullerton 61 | |||
| 18 Jan | UC Riverside | at | UC Irvine | |||
| 22 Jan | UC Irvine | at | Long Beach St | |||
| 25 Jan | Cal Poly | at | UC Irvine | |||
| 30 Jan | UC Irvine | at | UC Davis | |||
| 1 Feb | CS Fullerton | at | UC Irvine | |||
| 6 Feb | UC Davis | at | UC Irvine | |||
| 8 Feb | UC Irvine | at | UC Santa Barbara | |||
| 12 Feb | UC Irvine | at | UC Riverside | |||
| 16 Feb | UC Irvine | at | Hawaii | |||
| 19 Feb | Long Beach St | at | UC Irvine | |||
| 22 Feb | UC Irvine | at | CS Northridge | |||
| 27 Feb | UC Irvine | at | Cal Poly | |||
| 29 Feb | UC Santa Barbara | at | UC Irvine | |||
| 4 Mar | CS Northridge | at | UC Irvine |
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