| 18-Feb | California | 4 | vs | Houston | 2 | Scottsdale, AZ | |
| 19-Feb | San Diego St | 4 | vs | Houston | 3 | Scottsdale, AZ | |
| 20-Feb | TCU | 10 | vs | Houston | 0 | Scottsdale, AZ | |
| 22-Feb | Houston | 3 | at | McNeese St | 2 | ||
| 25-Feb | TX Southern | 4 | at | Houston | 11 | ||
| 27-Feb | UTRGV | 1 | at | Houston | 3 | ||
| 27-Feb | UTRGV | 10 | at | Houston | 16 | ||
| 1-Mar | Lamar | 5 | at | Houston | 6 | ||
| 4-Mar | Incarnate Word | 2 | at | Houston | 5 | ||
| 5-Mar | Incarnate Word | 13 | at | Houston | 8 | ||
| 6-Mar | Incarnate Word | 4 | at | Houston | 10 | ||
| 8-Mar | Houston | 10 | at | Rice | 7 | ||
| 9-Mar | Southern Univ | 4 | at | Houston | 7 | ||
| 11-Mar | Houston | 5 | at | Louisiana | 9 | ||
| 12-Mar | Houston | 8 | at | Louisiana | 4 | ||
| 13-Mar | Houston | 1 | at | Louisiana | 10 | ||
| 15-Mar | Houston | 8 | at | Texas A&M | 2 | ||
| 18-Mar | Columbia | 9 | at | Houston | 5 | ||
| 19-Mar | Columbia | 4 | at | Houston | 10 | ||
| 20-Mar | Columbia | 3 | at | Houston | 12 | ||
| 22-Mar | Houston | 9 | at | Sam Houston St | 1 | ||
| 25-Mar | W Carolina | 3 | at | Houston | 13 | ||
| 26-Mar | W Carolina | 6 | at | Houston | 3 | ||
| 27-Mar | W Carolina | 1 | at | Houston | 6 | ||
| 29-Mar | Prairie View | 1 | at | Houston | 13 | ||
| 1-Apr | Wichita St | 4 | at | Houston | 0 | ||
| 2-Apr | Wichita St | 3 | at | Houston | 5 | ||
| 3-Apr | Wichita St | 3 | at | Houston | 4 | ||
| 5-Apr | Sam Houston St | 6 | at | Houston | 8 | ||
| 8-Apr | Houston | 5 | at | Cincinnati | 4 | ||
| 9-Apr | Houston | 3 | at | Cincinnati | 13 | ||
| 10-Apr | Houston | 6 | at | Cincinnati | 9 | ||
| 12-Apr | UTRGV | 9 | at | Houston | 1 | ||
| 14-Apr | Tulane | 3 | at | Houston | 6 | ||
| 15-Apr | Tulane | 11 | at | Houston | 10 | ||
| 16-Apr | Tulane | 9 | at | Houston | 10 | ||
| 19-Apr | Houston Bap | 2 | at | Houston | 4 | ||
| 22-Apr | Memphis | 11 | at | Houston | 9 | ||
| 23-Apr | Memphis | 4 | at | Houston | 5 | ||
| 24-Apr | Memphis | 5 | at | Houston | 7 | ||
| 26-Apr | Houston | 1 | at | Lamar | 4 | ||
| 29-Apr | Houston | 6 | at | South Florida | 5 | ||
| 30-Apr | Houston | 13 | at | South Florida | 2 | ||
| 1-May | Houston | 9 | at | South Florida | 2 | ||
| 4-May | Rice | 2 | at | Houston | 8 | ||
| 6-May | Houston | 7 | at | Wichita St | 4 | ||
| 7-May | Houston | 4 | at | Wichita St | 12 | ||
| 8-May | Houston | 11 | at | Wichita St | 8 | ||
| 10-May | Houston | 9 | vs | Sam Houston St | 1 | Sugar Land, TX | |
| 13-May | UCF | 6 | at | Houston | 9 | ||
| 14-May | UCF | 6 | at | Houston | 5 | ||
| 15-May | UCF | 3 | at | Houston | 1 | ||
| 17-May | Rice | 5 | at | Houston | 4 | ||
| 19-May | Houston | 4 | at | East Carolina | 8 | ||
| 20-May | Houston | 3 | at | East Carolina | 5 | ||
| 21-May | Houston | 2 | at | East Carolina | 3 | ||
| 24-May | Houston | 10 | vs | Wichita St | 7 | Clearwater, FL | |
| 26-May | Houston | 8 | vs | Memphis | 7 | Clearwater, FL | |
| 28-May | Houston | 8 | at | UCF | 9 | Clearwater, FL | |
| 28-May | Houston | 9 | at | UCF | 6 | Clearwater, FL | |
| 29-May | East Carolina | 6 | vs | Houston | 1 | Clearwater, FL |