| 18-Feb | Louisville | 8 | vs | Charlotte | 7 | Tampa, FL | |
| 19-Feb | Louisville | 4 | at | South Florida | 8 | ||
| 20-Feb | Connecticut | 9 | vs | Louisville | 2 | Tampa, FL | |
| 21-Feb | Xavier | 6 | at | Louisville | 7 | ||
| 25-Feb | Dartmouth | 5 | at | Louisville | 19 | ||
| 26-Feb | Dartmouth | 6 | at | Louisville | 4 | ||
| 27-Feb | Dartmouth | 3 | at | Louisville | 16 | ||
| 1-Mar | Morehead St | 5 | at | Louisville | 7 | ||
| 4-Mar | Akron | 1 | at | Louisville | 9 | ||
| 5-Mar | Akron | 9 | at | Louisville | 22 | ||
| 5-Mar | Akron | 6 | at | Louisville | 20 | ||
| 8-Mar | TCU | 8 | at | Louisville | 9 | ||
| 11-Mar | Michigan | 16 | at | Louisville | 7 | ||
| 11-Mar | Michigan | 3 | at | Louisville | 5 | ||
| 13-Mar | Michigan | 1 | at | Louisville | 13 | ||
| 15-Mar | N Kentucky | 8 | at | Louisville | 12 | ||
| 16-Mar | Bellarmine | 5 | at | Louisville | 11 | ||
| 18-Mar | Notre Dame | 11 | at | Louisville | 16 | ||
| 19-Mar | Notre Dame | 1 | at | Louisville | 8 | ||
| 20-Mar | Notre Dame | 5 | at | Louisville | 7 | ||
| 22-Mar | Lipscomb | 6 | at | Louisville | 2 | ||
| 25-Mar | Louisville | 6 | at | Boston College | 1 | ||
| 26-Mar | Louisville | 10 | at | Boston College | 6 | ||
| 27-Mar | Louisville | 15 | at | Boston College | 1 | ||
| 29-Mar | Louisville | 16 | at | WKU | 6 | ||
| 2-Apr | Louisville | 7 | at | Pittsburgh | 8 | ||
| 2-Apr | Louisville | 14 | at | Pittsburgh | 6 | ||
| 3-Apr | Louisville | 3 | at | Pittsburgh | 6 | ||
| 8-Apr | North Carolina | 13 | at | Louisville | 9 | ||
| 9-Apr | North Carolina | 8 | at | Louisville | 9 | ||
| 10-Apr | North Carolina | 5 | at | Louisville | 6 | ||
| 12-Apr | Cincinnati | 10 | at | Louisville | 18 | ||
| 14-Apr | Louisville | 1 | at | Florida St | 8 | ||
| 15-Apr | Louisville | 4 | at | Florida St | 9 | ||
| 16-Apr | Louisville | 9 | at | Florida St | 10 | ||
| 19-Apr | Kentucky | 2 | at | Louisville | 4 | ||
| 22-Apr | NC State | 4 | at | Louisville | 11 | ||
| 23-Apr | NC State | 15 | at | Louisville | 10 | ||
| 24-Apr | NC State | 7 | at | Louisville | 11 | ||
| 26-Apr | WKU | 4 | at | Louisville | 11 | ||
| 29-Apr | Clemson | 2 | at | Louisville | 7 | ||
| 30-Apr | Clemson | 8 | at | Louisville | 10 | ||
| 1-May | Clemson | 15 | at | Louisville | 18 | ||
| 3-May | Louisville | 1 | at | Vanderbilt | 0 | ||
| 7-May | Louisville | 3 | at | Wake Forest | 14 | ||
| 7-May | Louisville | 6 | at | Wake Forest | 2 | ||
| 8-May | Louisville | 5 | at | Wake Forest | 5 | ||
| 10-May | Indiana | 2 | at | Louisville | 7 | ||
| 13-May | Louisville | 8 | at | Virginia Tech | 1 | ||
| 14-May | Louisville | 3 | at | Virginia Tech | 4 | ||
| 15-May | Louisville | 4 | at | Virginia Tech | 6 | ||
| 17-May | E Kentucky | 3 | at | Louisville | 10 | ||
| 19-May | Virginia | 1 | at | Louisville | 4 | ||
| 20-May | Virginia | 16 | at | Louisville | 7 | ||
| 21-May | Virginia | 3 | at | Louisville | 11 | ||
| 25-May | Pittsburgh | 6 | vs | Louisville | 5 | Charlotte, NC | |
| 26-May | Georgia Tech | 9 | vs | Louisville | 4 | Charlotte, NC | |
| 3-Jun | SE Missouri St | 2 | at | Louisville | 7 | ||
| 4-Jun | Louisville | 3 | at | Michigan | 7 | ||
| 5-Jun | Michigan | 1 | at | Louisville | 20 | ||
| 5-Jun | Louisville | 8 | at | Oregon | 5 | ||
| 6-Jun | Michigan | 9 | at | Louisville | 11 | ||
| 10-Jun | Louisville | 4 | at | Texas A&M | 5 | ||
| 11-Jun | Louisville | 3 | at | Texas A&M | 4 |