| 20-Feb | Mississippi St | 8 | vs | Texas | 3 | Arlington TX | |
| 21-Feb | TCU | 3 | vs | Mississippi St | 2 | Arlington TX | |
| 22-Feb | Mississippi St | 11 | vs | Texas Tech | 5 | Arlington TX | |
| 24-Feb | Jackson St | 3 | at | Mississippi St | 7 | ||
| 26-Feb | Tulane | 7 | at | Mississippi St | 3 | ||
| 27-Feb | Tulane | 5 | at | Mississippi St | 9 | ||
| 28-Feb | Tulane | 4 | at | Mississippi St | 5 | ||
| 3-Mar | Mississippi St | 4 | vs | Southern Miss | 1 | Pearl Miss. | |
| 5-Mar | Kent | 3 | at | Mississippi St | 8 | ||
| 6-Mar | Kent | 9 | at | Mississippi St | 5 | ||
| 7-Mar | Kent | 0 | at | Mississippi St | 13 | ||
| 9-Mar | Grambling | 0 | at | Mississippi St | 10 | ||
| 10-Mar | Louisiana | 0 | at | Mississippi St | 4 | ||
| 12-Mar | E Michigan | 0 | at | Mississippi St | 14 | ||
| 13-Mar | E Michigan | 1 | at | Mississippi St | 4 | ||
| 14-Mar | E Michigan | 1 | at | Mississippi St | 4 | ||
| 16-Mar | Samford | 2 | at | Mississippi St | 10 | ||
| 19-Mar | Mississippi St | 6 | at | LSU | 1 | ||
| 20-Mar | Mississippi St | 3 | at | LSU | 0 | ||
| 21-Mar | Mississippi St | 3 | at | LSU | 8 | ||
| 24-Mar | North Alabama | 1 | at | Mississippi St | 18 | ||
| 26-Mar | Arkansas | 8 | at | Mississippi St | 2 | ||
| 27-Mar | Arkansas | 11 | at | Mississippi St | 5 | ||
| 28-Mar | Arkansas | 6 | at | Mississippi St | 4 | ||
| 1-Apr | Kentucky | 1 | at | Mississippi St | 8 | ||
| 2-Apr | Kentucky | 2 | at | Mississippi St | 3 | ||
| 3-Apr | Kentucky | 3 | at | Mississippi St | 4 | ||
| 6-Apr | Southern Univ | 1 | at | Mississippi St | 15 | ||
| 9-Apr | Mississippi St | 6 | at | Auburn | 5 | ||
| 10-Apr | Mississippi St | 7 | at | Auburn | 2 | ||
| 11-Apr | Mississippi St | 19 | at | Auburn | 10 | ||
| 13-Apr | Arkansas St | 10 | at | Mississippi St | 18 | ||
| 16-Apr | Mississippi | 2 | at | Mississippi St | 5 | ||
| 17-Apr | Mississippi | 9 | at | Mississippi St | 0 | ||
| 18-Apr | Mississippi | 5 | at | Mississippi St | 7 | ||
| 20-Apr | UAB | 7 | at | Mississippi St | 19 | ||
| 23-Apr | Mississippi St | 2 | at | Vanderbilt | 6 | ||
| 24-Apr | Mississippi St | 7 | at | Vanderbilt | 4 | ||
| 25-Apr | Mississippi St | 4 | at | Vanderbilt | 7 | ||
| 30-Apr | Texas A&M | 7 | at | Mississippi St | 8 | ||
| 1-May | Texas A&M | 2 | at | Mississippi St | 3 | ||
| 1-May | Texas A&M | 5 | at | Mississippi St | 10 | ||
| 5-May | Mississippi St | 10 | at | Citadel | 2 | ||
| 7-May | Mississippi St | 9 | at | South Carolina | 0 | ||
| 8-May | Mississippi St | 9 | at | South Carolina | 6 | ||
| 9-May | Mississippi St | 3 | at | South Carolina | 4 | ||
| 13-May | Missouri | 4 | at | Mississippi St | 5 | ||
| 14-May | Missouri | 7 | at | Mississippi St | 6 | ||
| 15-May | Missouri | 16 | at | Mississippi St | 8 | ||
| 18-May | Jacksonville St | 1 | at | Mississippi St | 6 | ||
| 20-May | Mississippi St | 4 | at | Alabama | 2 | ||
| 21-May | Mississippi St | 7 | at | Alabama | 0 | ||
| 22-May | Mississippi St | 7 | at | Alabama | 3 | ||
| 26-May | Florida | 13 | vs | Mississippi St | 1 | Hoover AL | |
| 27-May | Tennessee | 12 | vs | Mississippi St | 2 | Hoover AL | |
| 4-Jun | Samford | 4 | vs | Mississippi St | 8 | Starkville Regional | |
| 5-Jun | VCU | 4 | vs | Mississippi St | 16 | Starkville Regional | |
| 7-Jun | Mississippi St | 6 | vs | Campbell | 5 | Starkville Regional (Mississippi St advances) | |
| 12-Jun | Notre Dame | 8 | vs | Mississippi St | 9 | Starkville | |
| 13-Jun | Mississippi St | 1 | vs | Notre Dame | 9 | Starkville | |
| 14-Jun | Notre Dame | 7 | vs | Mississippi St | 11 | Starkville (Mississippi St to CWS) | |
| 20-Jun | Mississippi St | 2 | vs | Texas | 1 | CWS #7 vs #2 | |
| 22-Jun | Mississippi St | 6 | vs | Virginia | 5 | Bracket 2 game 4 | |
| 25-Jun | Texas | 8 | vs | Mississippi St | 5 | Bracket 2 Game 6 | |
| 26-Jun | Texas | 3 | vs | Mississippi St | 4 | Bracket 2 Game 7 | |
| 28-Jun | Mississippi St | 2 | vs | Vanderbilt | 8 | "CWS Finals, game 1" | |
| 29-Jun | Vanderbilt | 2 | vs | Mississippi St | 13 | "CWS Finals, game 2" | |
| 30-Jun | Mississippi St | 9 | vs | Vanderbilt | 0 | CWS Championship |