| 17-Feb | Bucknell | 1 | at | Louisville | 7 | ||
| 18-Feb | Bucknell | 2 | at | Louisville | 11 | ||
| 19-Feb | Bucknell | 3 | at | Louisville | 5 | ||
| 22-Feb | Xavier | 8 | at | Louisville | 12 | ||
| 24-Feb | Bowling Green | 1 | at | Louisville | 2 | ||
| 25-Feb | Bowling Green | 9 | at | Louisville | 6 | ||
| 26-Feb | Bowling Green | 1 | at | Louisville | 14 | ||
| 28-Feb | E Kentucky | 0 | at | Louisville | 11 | ||
| 3-Mar | Louisville | 14 | vs | Texas A&M | 5 | Houston, TX | |
| 4-Mar | Louisville | 3 | vs | TCU | 2 | Houston, TX | |
| 5-Mar | Louisville | 10 | vs | Michigan | 0 | Houston, TX | |
| 7-Mar | Morehead St | 1 | at | Louisville | 11 | ||
| 10-Mar | Dayton | 7 | at | Louisville | 11 | ||
| 11-Mar | Dayton | 2 | at | Louisville | 6 | ||
| 12-Mar | Dayton | 1 | at | Louisville | 5 | ||
| 15-Mar | Miami OH | 4 | at | Louisville | 6 | ||
| 17-Mar | Georgia Tech | 7 | at | Louisville | 8 | ||
| 18-Mar | Georgia Tech | 10 | at | Louisville | 4 | ||
| 19-Mar | Georgia Tech | 3 | at | Louisville | 9 | ||
| 21-Mar | WKU | 8 | at | Louisville | 15 | ||
| 24-Mar | Louisville | 3 | at | Notre Dame | 4 | ||
| 26-Mar | Louisville | 2 | at | Notre Dame | 1 | ||
| 26-Mar | Louisville | 4 | at | Notre Dame | 5 | ||
| 28-Mar | Louisville | 14 | at | Cincinnati | 1 | ||
| 31-Mar | Louisville | 5 | at | NC State | 6 | ||
| 1-Apr | Louisville | 0 | at | NC State | 10 | ||
| 2-Apr | Louisville | 6 | at | NC State | 1 | ||
| 4-Apr | Lipscomb | 12 | at | Louisville | 7 | ||
| 6-Apr | Boston College | 4 | at | Louisville | 6 | ||
| 7-Apr | Boston College | 8 | at | Louisville | 9 | ||
| 8-Apr | Boston College | 2 | at | Louisville | 4 | ||
| 12-Apr | Bellarmine | 2 | at | Louisville | 14 | ||
| 14-Apr | Wake Forest | 11 | at | Louisville | 5 | ||
| 15-Apr | Wake Forest | 3 | at | Louisville | 0 | ||
| 16-Apr | Wake Forest | 2 | at | Louisville | 7 | ||
| 18-Apr | Louisville | 3 | at | Indiana | 7 | ||
| 21-Apr | Louisville | 9 | at | Duke | 10 | ||
| 22-Apr | Louisville | 6 | at | Duke | 7 | ||
| 23-Apr | Louisville | 3 | at | Duke | 4 | ||
| 25-Apr | Louisville | 7 | at | Kentucky | 0 | ||
| 27-Apr | Miami FL | 6 | at | Louisville | 5 | ||
| 28-Apr | Miami FL | 0 | at | Louisville | 11 | ||
| 29-Apr | Miami FL | 10 | at | Louisville | 7 | ||
| 2-May | Louisville | 18 | at | Bellarmine | 7 | ||
| 5-May | Louisville | 3 | at | Clemson | 6 | ||
| 6-May | Louisville | 3 | at | Clemson | 4 | ||
| 7-May | Louisville | 3 | at | Clemson | 7 | ||
| 9-May | Vanderbilt | 12 | at | Louisville | 8 | ||
| 12-May | Louisville | 5 | at | Virginia | 15 | ||
| 13-May | Louisville | 1 | at | Virginia | 4 | ||
| 14-May | Louisville | 3 | at | Virginia | 8 | ||
| 16-May | N Kentucky | 5 | at | Louisville | 18 | ||
| 18-May | Florida St | 4 | at | Louisville | 7 | ||
| 19-May | Florida St | 7 | at | Louisville | 4 | ||
| 20-May | Florida St | 6 | at | Louisville | 2 |