| 8 Nov | Dartmouth 68 | at | Buffalo 63 | vs Ivy | ||
| 11 Nov | Nazareth 72 | at | Buffalo 109 | vs ND1 | ||
| 16 Nov | Buffalo 88 | vs | Harvard 76 | Toronto, ON | vs Ivy | |
| 21 Nov | Connecticut 79 | vs | Buffalo 68 | Charleston, SC | vs AAC | |
| 22 Nov | Buffalo 76 | vs | Towson 73 | Charleston, SC | vs CAA | |
| 24 Nov | Buffalo 75 | vs | Missouri St 74 | Charleston, SC | vs MVC | |
| 30 Nov | William & Mary 77 | at | Buffalo 88 | vs CAA | ||
| 3 Dec | Buffalo 76 | at | Vanderbilt 90 | at SEC | ||
| 8 Dec | Buffalo 74 | at | DePaul 69 | at BE | ||
| 14 Dec | Army 89 | at | Buffalo 76 | vs PL | ||
| 18 Dec | Canisius 73 | at | Buffalo 82 | vs MAAC | ||
| 21 Dec | Niagara 72 | at | Buffalo 92 | vs MAAC | ||
| 30 Dec | St Bonaventure 79 | at | Buffalo 84 | vs A10 | ||
| 4 Jan | N Illinois 73 | at | Buffalo 72 | |||
| 7 Jan | Buffalo 68 | at | Ball St 88 | |||
| 10 Jan | Buffalo 83 | at | Miami OH 78 | |||
| 14 Jan | Ohio 73 | at | Buffalo 76 | |||
| 18 Jan | Buffalo | at | C Michigan | |||
| 21 Jan | W Michigan | at | Buffalo | |||
| 24 Jan | Kent | at | Buffalo | |||
| 28 Jan | Buffalo | at | Akron | |||
| 31 Jan | Bowling Green | at | Buffalo | |||
| 4 Feb | Buffalo | at | E Michigan | |||
| 8 Feb | C Michigan | at | Buffalo | |||
| 15 Feb | Buffalo | at | Toledo | |||
| 18 Feb | Ball St | at | Buffalo | |||
| 22 Feb | Buffalo | at | Kent | |||
| 25 Feb | Buffalo | at | Ohio | |||
| 29 Feb | Akron | at | Buffalo | |||
| 3 Mar | Miami OH | at | Buffalo | |||
| 6 Mar | Buffalo | at | Bowling Green |
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