| 6 Nov | Oral Roberts 75 | at | Oklahoma St 80 | vs SL | ||
| 9 Nov | Missouri KC 51 | at | Oklahoma St 69 | vs WAC | ||
| 13 Nov | Oklahoma St 73 | at | Col Charleston 54 | at CAA | ||
| 17 Nov | Yale 57 | at | Oklahoma St 64 | vs Ivy | ||
| 22 Nov | W Michigan 63 | at | Oklahoma St 70 | vs MAC | ||
| 27 Nov | Oklahoma St 86 | vs | Syracuse 72 | Brooklyn, NY | vs ACC | |
| 29 Nov | Oklahoma St 78 | vs | Mississippi 37 | Brooklyn, NY | vs SEC | |
| 4 Dec | Georgetown 81 | at | Oklahoma St 74 | vs BE | ||
| 8 Dec | Wichita St 80 | at | Oklahoma St 61 | vs AAC | ||
| 15 Dec | Oklahoma St 61 | at | Houston 55 | at AAC | ||
| 21 Dec | Minnesota 86 | vs | Oklahoma St 66 | Tulsa, OK | vs B10 | |
| 29 Dec | SE Louisiana 31 | at | Oklahoma St 82 | vs SLC | ||
| 4 Jan | Oklahoma St 50 | at | Texas Tech 85 | |||
| 6 Jan | West Virginia 55 | at | Oklahoma St 41 | |||
| 11 Jan | Oklahoma St 40 | at | TCU 52 | |||
| 15 Jan | Texas 76 | at | Oklahoma St 64 | |||
| 18 Jan | Baylor | at | Oklahoma St | |||
| 21 Jan | Oklahoma St | at | Iowa St | |||
| 25 Jan | Oklahoma St | at | Texas A&M | at SEC | ||
| 27 Jan | Kansas | at | Oklahoma St | |||
| 1 Feb | Oklahoma St | at | Oklahoma | |||
| 5 Feb | TCU | at | Oklahoma St | |||
| 8 Feb | Oklahoma St | at | Baylor | |||
| 11 Feb | Oklahoma St | at | Kansas St | |||
| 15 Feb | Texas Tech | at | Oklahoma St | |||
| 18 Feb | Oklahoma St | at | West Virginia | |||
| 22 Feb | Oklahoma | at | Oklahoma St | |||
| 24 Feb | Oklahoma St | at | Kansas | |||
| 29 Feb | Iowa St | at | Oklahoma St | |||
| 4 Mar | Kansas St | at | Oklahoma St | |||
| 7 Mar | Oklahoma St | at | Texas |
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